Denver, Colorado · Telehealth in CO & CA
Compassionate, Collaborative and Integrative Care
At Centerpoint Integrative Psychiatry, we help individuals return to their center — a place of greater balance, compassion, resilience, and inner stability.
We provide trauma-informed, integrative psychiatric care that thoughtfully incorporates ketamine-assisted psychotherapy and psychedelic-informed perspectives alongside evidence-based psychiatric treatment. By attending to the biological, emotional, relational, and existential dimensions of life, we support healing, self-understanding, and meaningful change.
Life is difficult. This is a great truth, one of the greatest truths. It is a great truth because once we truly see this truth, we transcend it.
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— M. Scott Peck
What We Offer
Care offerings designed to support healing at every stage — from symptom relief and stabilization to deeper emotional work and lasting transformation.
Thoughtful, collaborative prescribing when medication is helpful, and careful deprescribing when it is no longer serving your goals. We view psychiatric medications as one tool among many — sometimes an essential part of healing, and sometimes only one piece of a larger picture.
Includes De-prescribing → 02A personalized approach that blends psychodynamic psychotherapy, Jungian and depth-oriented perspectives, mindfulness-based therapies, and somatically informed approaches. Together, we explore patterns, meaning, emotional healing, and personal growth.
Holistic · Preparation & Integration → 03Compassionate addiction treatment grounded in harm reduction, medication-assisted treatment, and realistic goal-setting. We help patients understand the underlying forces that sustain addictive behaviors while supporting meaningful and lasting change.
SUD & Addictive Disorders → 04Physician-supervised ketamine treatment structured around preparation, medicine sessions, and integration. Delivered through sublingual lozenges or intramuscular ketamine, with careful attention to set, setting, safety, and the therapeutic process.
Sublingual · IM · Learn More →Who We Serve
Many who find their way here have tried conventional approaches and sensed that something important was still missing. We meet you where you are and offer compassionate, individualized care that honors your unique story while drawing from the best available evidence-based treatments. Our work recognizes the complexity of human suffering and healing, attending not only to symptoms, but also to the deeper patterns, relationships, and experiences that shape a meaningful life.
Our Approach
We begin from the belief that every person possesses an innate capacity for healing and growth when provided with the right tools, support, and environment. Our role is not simply to treat symptoms, but to help create the conditions in which healing can unfold.
We view healing as more than the reduction of a diagnosis or a disorder. It involves understanding the whole person — their biology, their rhythm, temperament, their relationships, life experiences, values, and sense of meaning. By caring for the full human being, we aim to support not only symptom relief, but also greater resilience, connection, and well-being.
These three stages guide our treatment approach:
Karim Lotfy, MD
Meet Your Psychiatrist
Integrative Psychiatrist · Founder of Centerpoint
Dr. Lotfy practices psychiatry as both a science and a passionate human encounter. His work joins rigorous medical training with a belief that suffering carries meaning worth understanding — not only symptoms worth suppressing.
He brings together psychopharmacology, addiction medicine, lifestyle medicine, somatic and depth-oriented therapy, and ketamine-assisted psychotherapy into one integrated practice — meeting each person where they are, and walking with them toward where they want to go.
Read Full BioGetting Started
The first step is a conversation. We'll talk through what has brought you here, what you've already tried, and whether Centerpoint is the right fit.
